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Constitutively Active Artemis Nuclease Recognizes Structures Containing Single-Stranded DNA Configurations
The Artemis nuclease recognizes and endonucleolytically cleaves at single-stranded to double-stranded DNA (ss/dsDNA) boundaries. It is also a key enzyme in the non-homologous end joining (NHEJ) DNA double-strand break repair pathway. Previously, a truncated form, Artemis-413, was developed that is c...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6801081/ https://ncbi.nlm.nih.gov/pubmed/31377101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2019.102676 |
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