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DNA-PKcs Regulates a Single-stranded DNA Endonuclease Activity of Artemis
Human nuclease Artemis belongs to the metallo-beta-lactamase protein family. It acquires double-stranded DNA endonuclease activity in the presence of DNA-PKcs. This double-stranded DNA endonuclease activity is critical for opening DNA hairpins in V(D)J recombination and is thought to be important fo...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847011/ https://ncbi.nlm.nih.gov/pubmed/20117966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.01.001 |
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