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Evidence That the DNA Endonuclease ARTEMIS also Has Intrinsic 5′-Exonuclease Activity
ARTEMIS is a member of the metallo-β-lactamase protein family. ARTEMIS has endonuclease activity at DNA hairpins and at 5′- and 3′-DNA overhangs of duplex DNA, and this endonucleolytic activity is dependent upon DNA-PKcs. There has been uncertainty about whether ARTEMIS also has 5′-exonuclease activ...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953294/ https://ncbi.nlm.nih.gov/pubmed/24500713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.544874 |
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