Polynucleotide Kinase and Aprataxin-like Forkhead-associated Protein (PALF) Acts as Both a Single-stranded DNA Endonuclease and a Single-Stranded DNA 3′ Exonuclease and Can Participate in DNA End Joining in a Biochemical System

Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF, also called aprataxin- and PNK-like factor (APLF)) has been shown to have nuclease activity and to use its forkhead-associated domain to bind to x-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4)....

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Detalhes bibliográficos
Main Authors: Li, Sicong, Kanno, Shin-ichiro, Watanabe, Reiko, Ogiwara, Hideaki, Kohno, Takashi, Watanabe, Go, Yasui, Akira, Lieber, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196146/
https://ncbi.nlm.nih.gov/pubmed/21885877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287797
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