Polynucleotide phosphorylase exonuclease and polymerase activities on single-stranded DNA ends are modulated by RecN, SsbA and RecA proteins

Bacillus subtilis pnpA gene product, polynucleotide phosphorylase (PNPase), is involved in double-strand break (DSB) repair via homologous recombination (HR) or non-homologous end-joining (NHEJ). RecN is among the first responders to localize at the DNA DSBs, with PNPase facilitating the formation o...

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Bibliografske podrobnosti
Main Authors: Cardenas, Paula P., Carzaniga, Thomas, Zangrossi, Sandro, Briani, Federica, Garcia-Tirado, Esther, Dehò, Gianni, Alonso, Juan C.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241651/
https://ncbi.nlm.nih.gov/pubmed/21859751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr635
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