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Polynucleotide phosphorylase is implicated in homologous recombination and DNA repair in Escherichia coli

BACKGROUND: Polynucleotide phosphorylase (PNPase, encoded by pnp) is generally thought of as an enzyme dedicated to RNA metabolism. The pleiotropic effects of PNPase deficiency is imputed to altered processing and turnover of mRNAs and small RNAs, which in turn leads to aberrant gene expression. How...

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Détails bibliographiques
Publié dans:BMC Microbiol
Auteurs principaux: Carzaniga, Thomas, Sbarufatti, Giulia, Briani, Federica, Dehò, Gianni
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379764/
https://ncbi.nlm.nih.gov/pubmed/28376742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-017-0980-z
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