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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

During V(D)J recombination, the RAG1 and RAG2 proteins form a complex and initiate the process of rearrangement by cleaving between the coding and signal segments and generating hairpins at the coding ends. Prior to ligation of the coding ends by DNA ligase IV/XRCC4, these hairpins are opened by the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Pannicke, Ulrich, Ma, Yunmei, Hopfner, Karl-Peter, Niewolik, Doris, Lieber, Michael R, Schwarz, Klaus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC404326/
https://ncbi.nlm.nih.gov/pubmed/15071507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600206
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