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Functional and biochemical dissection of the structure-specific nuclease ARTEMIS

During V(D)J recombination, the RAG1 and RAG2 proteins form a complex and initiate the process of rearrangement by cleaving between the coding and signal segments and generating hairpins at the coding ends. Prior to ligation of the coding ends by DNA ligase IV/XRCC4, these hairpins are opened by the...

詳細記述

保存先:
書誌詳細
主要な著者: Pannicke, Ulrich, Ma, Yunmei, Hopfner, Karl-Peter, Niewolik, Doris, Lieber, Michael R, Schwarz, Klaus
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC404326/
https://ncbi.nlm.nih.gov/pubmed/15071507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600206
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