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Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis
The rise in incidence and prevalence of eosinophilic esophagitis (EoE) since the 1990s has promoted investigations into its pathogenesis, natural history, and management. Identified genetic variants in FLG, DSG1, CAPN14, SPINK5, and SPINK7 link EoE to epithelial barrier dysfunction, whereas variants...
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| 出版年: | Curr Opin Immunol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800613/ https://ncbi.nlm.nih.gov/pubmed/31132551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.04.004 |
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