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Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis
The rise in incidence and prevalence of eosinophilic esophagitis (EoE) since the 1990s has promoted investigations into its pathogenesis, natural history, and management. Identified genetic variants in FLG, DSG1, CAPN14, SPINK5, and SPINK7 link EoE to epithelial barrier dysfunction, whereas variants...
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| Publicado en: | Curr Opin Immunol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800613/ https://ncbi.nlm.nih.gov/pubmed/31132551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.04.004 |
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