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Role of genetics, environment, and their interactions in the pathogenesis of eosinophilic esophagitis

The rise in incidence and prevalence of eosinophilic esophagitis (EoE) since the 1990s has promoted investigations into its pathogenesis, natural history, and management. Identified genetic variants in FLG, DSG1, CAPN14, SPINK5, and SPINK7 link EoE to epithelial barrier dysfunction, whereas variants...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Curr Opin Immunol
Egile Nagusiak: Lyles, John, Rothenberg, Marc
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800613/
https://ncbi.nlm.nih.gov/pubmed/31132551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.04.004
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