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Methods to Study Trinucleotide Repeat Instability Induced by DNA Damage and Repair

Trinucleotide repeat (TNR) instability (expansion and deletion) is associated with more than 42 human neurodegenerative diseases and cancer and mediated by DNA replication, repair, recombination, and gene transcription. Somatic TNR instability is involved in the progression of TNR expansion diseases...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Lai, Yanhao, Lei, Ruipeng, Ren, Yaou, Liu, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800170/
https://ncbi.nlm.nih.gov/pubmed/31127571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9500-4_5
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