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Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q
Trinucleotide repeat (TNR) instability is associated with human neurodegenerative diseases and cancer. Recent studies have pointed out that DNA base excision repair (BER) mediated by DNA polymerase β (pol β) plays a crucial role in governing somatic TNR instability in a damage-location dependent man...
Shranjeno v:
| izdano v: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5419657/ https://ncbi.nlm.nih.gov/pubmed/28475635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177299 |
| Oznake: |
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