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3012 Functional consequences of pravastatin isomerization on OATP1B1-mediated transport
OBJECTIVES/SPECIFIC AIMS: In the present study, we examined the functional consequences of 3α-PVA on OATP1B1-mediated PVA transport. To elucidate this, we determined the effect of SLCO1B1 genotype on PVA transport and the role of 3αPVA as a competitive inhibitor of OATP1B1, which could serve as anot...
Kaydedildi:
| Yayımlandı: | J Clin Transl Sci |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cambridge University Press
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6799086/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.243 |
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