Polyubiquitin Chains Linked by Lysine Residue 48 (K48) Selectively Target Oxidized Proteins In Vivo

Aims: Ubiquitin is a highly conserved protein modifier that heavily accumulates during the oxidative stress response. Here, we investigated the role of the ubiquitination system, particularly at the linkage level, in the degradation of oxidized proteins. The function of ubiquitin in the removal of o...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Manohar, Sandhya, Jacob, Samson, Wang, Jade, Wiechecki, Keira A., Koh, Hiromi W.L., Simões, Vanessa, Choi, Hyungwon, Vogel, Christine, Silva, Gustavo M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798811/
https://ncbi.nlm.nih.gov/pubmed/31482721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2019.7826
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