Mechanism of Lysine 48 Selectivity during Polyubiquitin Chain Formation by the Ube2R1/2 Ubiquitin-Conjugating Enzyme

Lysine selectivity is of critical importance during polyubiquitin chain formation because the identity of the lysine controls the biological outcome. Ubiquitins are covalently linked in polyubiquitin chains through one of seven lysine residues on its surface and the C terminus of adjacent protomers....

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Hill, Spencer, Harrison, Joseph S., Lewis, Steven M., Kuhlman, Brian, Kleiger, Gary
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959314/
https://ncbi.nlm.nih.gov/pubmed/27044868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00097-16
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