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The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines
The ubiquitin-proteasome pathway plays a crucial role in many cellular processes by degrading substrates tagged by polyubiquitin chains, linked mostly through lysine 48 of ubiquitin. Although polymerization of ubiquitin via its six other lysine residues exists in vivo as part of various physiologica...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838281/ https://ncbi.nlm.nih.gov/pubmed/20061386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.089003 |
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