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The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K
The post-translational modification of proteins by ubiquitin is central to the regulation of eukaryotic cells. Substrate-bound ubiquitin chains linked by lysine 11 and 48 target proteins to the proteasome for degradation and determine protein abundance in cells, while other ubiquitin chain linkages...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4655369/ https://ncbi.nlm.nih.gov/pubmed/26592444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16793 |
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