The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains

The assembly of a specific polymeric ubiquitin chain on a target protein is a key event in the regulation of numerous cellular processes. Yet, the mechanisms that govern the selective synthesis of particular polyubiquitin signals remain enigmatic. The homologous ubiquitin‐conjugating (E2) enzymes Ub...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Pluska, Lukas, Jarosch, Ernst, Zauber, Henrik, Kniss, Andreas, Waltho, Anita, Bagola, Katrin, von Delbrück, Maximilian, Löhr, Frank, Schulman, Brenda A, Selbach, Matthias, Dötsch, Volker, Sommer, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957398/
https://ncbi.nlm.nih.gov/pubmed/33576509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106094
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