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Ubiquitin-conjugating Enzyme Cdc34 and Ubiquitin Ligase Skp1-Cullin-F-box Ligase (SCF) Interact through Multiple Conformations

In the ubiquitin-proteasome system, protein substrates are degraded via covalent modification by a polyubiquitin chain. The polyubiquitin chain must be assembled rapidly in cells, because a chain of at least four ubiquitins is required to signal for degradation, and chain-editing enzymes in the cell...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sandoval, Daniella, Hill, Spencer, Ziemba, Amy, Lewis, Steven, Kuhlman, Brian, Kleiger, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294478/
https://ncbi.nlm.nih.gov/pubmed/25425648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615559
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