The Acidic Tail of the Cdc34 Ubiquitin-conjugating Enzyme Functions in Both Binding to and Catalysis with Ubiquitin Ligase SCF(Cdc4)

Ubiquitin ligases, together with their cognate ubiquitin-conjugating enzymes, are responsible for the ubiquitylation of proteins, a process that regulates a myriad of eukaryotic cellular functions. The first cullin-RING ligase discovered, yeast SCF(Cdc4), functions with the conjugating enzyme Cdc34...

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Bibliographische Detailangaben
Hauptverfasser: Kleiger, Gary, Hao, Bing, Mohl, Dane A., Deshaies, Raymond J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Protein Synthesis, Post-Translational Modification, and Degradation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794717/
https://ncbi.nlm.nih.gov/pubmed/19875449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.058529
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