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Regulation of neddylation and deneddylation of cullin1 in SCF(Skp2) ubiquitin ligase by F-box protein and substrate
The activity of cullin-containing ubiquitin protein ligase complexes is stimulated by linkage to cullin of the ubiquitin-like protein Nedd8 (“neddylation”). Neddylation is inhibited by the tight binding of cullins to CAND1 (cullin-associated and neddylation-dissociated 1) protein, and Nedd8 is remov...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544201/ https://ncbi.nlm.nih.gov/pubmed/16861300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603921103 |
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