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Purification, crystallization and preliminary crystallographic studies of Lys48-linked polyubiquitin chains

Post-translational modification of proteins by covalent attachment of ubiquitin regulates diverse cellular events. A Lys48-linked polyubiquitin chain is formed via an isopeptide bond between Lys48 and the C-terminal Gly76 of different ubiquitin molecules. The chain is attached to a lysine residue of...

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Bibliografiske detaljer
Main Authors: Morimoto, Daichi, Isogai, Shin, Tenno, Takeshi, Tochio, Hidehito, Shirakawa, Masahiro, Ariyoshi, Mariko
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898474/
https://ncbi.nlm.nih.gov/pubmed/20606286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110018804
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