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Mechanism of Lys48-linked polyubiquitin chain recognition by the Mud1 UBA domain
The ubiquitin-pathway associated (UBA) domain is a 40-residue polyubiquitin-binding motif. The Schizosaccharomyces pombe protein Mud1 is an ortholog of the Saccharomyces cerevisiae DNA-damage response protein Ddi1 and binds to K48-linked polyubiquitin through its UBA domain. We have solved the cryst...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224687/ https://ncbi.nlm.nih.gov/pubmed/16138082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600797 |
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