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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

At least eight types of ubiquitin chain exist, and individual linkages affect distinct cellular processes. The only distinguishing feature of differently linked ubiquitin chains is their structure, as polymers of the same unit are chemically identical. Here, we have crystallized Lys 63-linked and li...

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Hlavní autoři: Komander, David, Reyes-Turcu, Francisca, Licchesi, Julien D F, Odenwaelder, Peter, Wilkinson, Keith D, Barford, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680876/
https://ncbi.nlm.nih.gov/pubmed/19373254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.55
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