Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

At least eight types of ubiquitin chain exist, and individual linkages affect distinct cellular processes. The only distinguishing feature of differently linked ubiquitin chains is their structure, as polymers of the same unit are chemically identical. Here, we have crystallized Lys 63-linked and li...

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Bibliografiske detaljer
Main Authors: Komander, David, Reyes-Turcu, Francisca, Licchesi, Julien D F, Odenwaelder, Peter, Wilkinson, Keith D, Barford, David
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680876/
https://ncbi.nlm.nih.gov/pubmed/19373254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.55
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