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Mitochondrial accumulation of polyubiquitinated proteins and differential regulation of apoptosis by polyubiquitination sites Lys‐48 and ‐63

Proteins tagged with lysine (Lys, K) 48 polyubiquitins chains are destined for degradation by the 26S proteasomal system. Impairment of the ubiquitin proteasome system (UPS) function culminates in the accumulation of polyubiquitinated proteins in many neurodegenerative conditions including Parkinson...

詳細記述

保存先:
書誌詳細
主要な著者: Sun, Faneng, Kanthasamy, Arthi, Anantharam, Vellareddy, Kanthasamy, Anumantha G.
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819597/
https://ncbi.nlm.nih.gov/pubmed/19432818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00775.x
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