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Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T

The conjugation of polyubiquitin to target proteins acts as a signal that regulates target stability, localization, and function. Several ubiquitin binding domains have been described, and while much is known about ubiquitin binding to the isolated domains, little is known with regard to how the dom...

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Autors principals: Reyes-Turcu, Francisca E., Shanks, John R., Komander, David, Wilkinson, Keith D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443676/
https://ncbi.nlm.nih.gov/pubmed/18482987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800947200
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