Small Ubiquitin-related Modifier (SUMO) Binding Determines Substrate Recognition and Paralog-selective SUMO Modification

Small ubiquitin-related modifiers (SUMOs) regulate diverse cellular processes through their covalent attachment to target proteins. Vertebrates express three SUMO paralogs: SUMO-1, SUMO-2, and SUMO-3 (SUMO-2 and SUMO-3 are ∼96% identical and referred to as SUMO-2/3). SUMO-1 and SUMO-2/3 are conjugat...

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Hlavní autoři: Zhu, Jianmei, Zhu, Shanshan, Guzzo, Catherine M., Ellis, Nathan A., Sung, Ki Sa, Choi, Cheol Yong, Matunis, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Protein Synthesis, Post-Translational Modification, and Degradation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570875/
https://ncbi.nlm.nih.gov/pubmed/18708356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803632200
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