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Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
RAP80 has a key role in the recruitment of the Abraxas–BRCC36–BRCA1–BARD1 complex to DNA-damage foci for DNA repair through specific recognition of Lys 63-linked polyubiquitinated proteins by its tandem ubiquitin-interacting motifs (UIMs). Here, we report the crystal structure of the RAP80 tandem UI...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735169/ https://ncbi.nlm.nih.gov/pubmed/19536136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.160 |
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