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Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

The linear ubiquitin chain assembly complex (LUBAC) is a key nuclear factor-κB (NF-κB) pathway component that produces linear polyubiquitin chains. The HOIL-1L subunit of LUBAC has been shown to bind linear chains; however, detailed structural and functional analyses on the binding between LUBAC and...

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Bibliografiske detaljer
Main Authors: Sato, Yusuke, Fujita, Hiroaki, Yoshikawa, Azusa, Yamashita, Masami, Yamagata, Atsushi, Kaiser, Stephen E., Iwai, Kazuhiro, Fukai, Shuya
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251058/
https://ncbi.nlm.nih.gov/pubmed/22139374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109088108
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