Solution Structure of the Ubiquitin-associated (UBA) Domain of Human Autophagy Receptor NBR1 and Its Interaction with Ubiquitin and Polyubiquitin

NBR1 (neighbor of BRCA1 gene 1) is a protein commonly found in ubiquitin-positive inclusions in neurodegenerative diseases. Due to its high architectural similarity to the well studied autophagy receptor protein p62/SQSTM1, NBR1 has been thought to analogously bind to ubiquitin-marked autophagic sub...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Walinda, Erik, Morimoto, Daichi, Sugase, Kenji, Konuma, Tsuyoshi, Tochio, Hidehito, Shirakawa, Masahiro
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Biochemistry and Molecular Biology 2014
الموضوعات:
Protein Synthesis and Degradation
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022861/
https://ncbi.nlm.nih.gov/pubmed/24692539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.555441
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