Hydrogen-Deuterium Exchange Profiles of Polyubiquitin Fibrils

Ubiquitin and its polymeric forms are conjugated to intracellular proteins to regulate diverse intracellular processes. Intriguingly, polyubiquitin has also been identified as a component of pathological protein aggregates associated with Alzheimer’s disease and other neurodegenerative disorders. We...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Morimoto, Daichi, Nishizawa, Ryo, Walinda, Erik, Takashima, Shingo, Sugase, Kenji, Shirakawa, Masahiro
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414897/
https://ncbi.nlm.nih.gov/pubmed/30966275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym10030240
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