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Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin

p62/SQSTM1/A170 is a multimodular protein that is found in ubiquitin-positive inclusions associated with neurodegenerative diseases. Recent findings indicate that p62 mediates the interaction between ubiquitinated proteins and autophagosomes, leading these proteins to be degraded via the autophagy-l...

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Detalhes bibliográficos
Main Authors: Isogai, Shin, Morimoto, Daichi, Arita, Kyohei, Unzai, Satoru, Tenno, Takeshi, Hasegawa, Jun, Sou, Yu-shin, Komatsu, Masaaki, Tanaka, Keiji, Shirakawa, Masahiro, Tochio, Hidehito
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173063/
https://ncbi.nlm.nih.gov/pubmed/21715324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259630
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