The Vaccinia Virus (VACV) B1 and Cellular VRK2 Kinases Promote VACV Replication Factory Formation through Phosphorylation-Dependent Inhibition of VACV B12

Comparative examination of viral and host protein homologs reveals novel mechanisms governing downstream signaling effectors of both cellular and viral origin. The vaccinia virus B1 protein kinase is involved in promoting multiple facets of the virus life cycle and is a homolog of three conserved ce...

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Pubblicato in:J Virol
Autori principali: Rico, Amber B., Wang, Zhigang, Olson, Annabel T., Linville, Alexandria C., Bullard, Brianna L., Weaver, Eric A., Jones, Clinton, Wiebe, Matthew S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798115/
https://ncbi.nlm.nih.gov/pubmed/31341052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00855-19
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