Parainfluenza virus 5-based vaccine vectors expressing vaccinia virus (VACV) antigens provide long-term protection in mice from lethal intranasal VACV challenge

To test the potential for parainfluenza virus 5 (PIV5)-based vectors to provide protection from vaccinia virus (VACV) infection, PIV5 was engineered to express secreted VACV L1R and B5R proteins, two important antigens for neutralization of intracellular mature (IMV) and extracellular enveloped (EEV...

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Detalhes bibliográficos
Main Authors: Clark, Kimberly M., Johnson, John B., Kock, Nancy D., Mizel, Steven B., Parks, Griffith D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177979/
https://ncbi.nlm.nih.gov/pubmed/21885079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.08.005
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