LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

Dendritic cells (DCs) play a pivotal role in priming adaptive immunity. However, the involvement of DCs in controlling excessive and deleterious T cell responses remains poorly defined. Moreover, the metabolic dependence and regulation of DC function are unclear. Here we show that LKB1 signaling in...

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Udgivet i:Cell Res
Main Authors: Wang, Yanyan, Du, Xingrong, Wei, Jun, Long, Lingyun, Tan, Haiyan, Guy, Cliff, Dhungana, Yogesh, Qian, Chenxi, Neale, Geoffrey, Fu, Yang-Xin, Yu, Jiyang, Peng, Junmin, Chi, Hongbo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796952/
https://ncbi.nlm.nih.gov/pubmed/30911060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0157-4
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