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Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions
Invariant natural killer T (iNKT) cells acquire effector functions during development by mechanisms that remain poorly understood. Here, we show that the Hippo kinases Mst1 and Mst2 act as molecular rheostats for the terminal maturation and effector differentiation programs of iNKT cells. Loss of Ms...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7971129/ https://ncbi.nlm.nih.gov/pubmed/32289155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191157 |
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