Prdx4 limits caspase‐1 activation and restricts inflammasome‐mediated signaling by extracellular vesicles

Inflammasomes are cytosolic protein complexes, which orchestrate the maturation of active IL‐1β by proteolytic cleavage via caspase‐1. Although many principles of inflammasome activation have been described, mechanisms that limit inflammasome‐dependent immune responses remain poorly defined. Here, w...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Lipinski, Simone, Pfeuffer, Steffen, Arnold, Philipp, Treitz, Christian, Aden, Konrad, Ebsen, Henriette, Falk‐Paulsen, Maren, Gisch, Nicolas, Fazio, Antonella, Kuiper, Jan, Luzius, Anne, Billmann‐Born, Susanne, Schreiber, Stefan, Nuñez, Gabriel, Beer, Hans‐Dietmar, Strowig, Till, Lamkanfi, Mohamed, Tholey, Andreas, Rosenstiel, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792017/
https://ncbi.nlm.nih.gov/pubmed/31544965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101266
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