DNA methyltransferase inhibition reduces inflammation-induced colon tumorigenesis

Chronic inflammation is strongly associated with an increased risk of developing colorectal cancer. DNA hypermethylation of CpG islands alters the expression of genes in cancer cells and plays an important role in carcinogenesis. Chronic inflammation is also associated with DNA methylation alteratio...

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Опубликовано в: :Epigenetics
Главные авторы: Maiuri, Ashley R., Savant, Sudha S., Podicheti, Ram, Rusch, Douglas B., O’Hagan, Heather M.
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2019
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791707/
https://ncbi.nlm.nih.gov/pubmed/31240997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1634986
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