Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy

Colorectal cancer (CRC) is multi-faceted with subtypes defined by genetic, histological, and immunologic features which are potentially influenced by inflammation, mutagens, and/or microbiota. CRCs with activating mutations in BRAF are associated with distinct clinical characteristics though the pat...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Cancer Discov
Główni autorzy: DeStefano Shields, Christina E., White, James R., Chung, Liam, Wenzel, Alyssa, Hicks, Jessica L., Tam, Ada J., Chan, June L., Dejea, Christine M., Fan, Hongni, Michel, John, Maiuri, Ashley R., Sriramkumar, Shruthi, Podicheti, Ram, Rusch, Douglas B., Wang, Hao, De Marzo, Angelo M., Besharati, Sepideh, Anders, Robert A., Baylin, Stephen B., O’Hagan, Heather M., Housseau, Franck, Sears, Cynthia L.
Format: Artigo
Język:Inglês
Wydane: 2021
Hasła przedmiotowe:
Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295175/
https://ncbi.nlm.nih.gov/pubmed/33632774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0770
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy