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Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy
Colorectal cancer (CRC) is multi-faceted with subtypes defined by genetic, histological, and immunologic features which are potentially influenced by inflammation, mutagens, and/or microbiota. CRCs with activating mutations in BRAF are associated with distinct clinical characteristics though the pat...
Zapisane w:
| Wydane w: | Cancer Discov |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8295175/ https://ncbi.nlm.nih.gov/pubmed/33632774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-0770 |
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