Mismatch Repair Proteins Initiate Epigenetic Alterations During Inflammation-Driven Tumorigenesis

Aberrant silencing of genes by DNA methylation contributes to cancer, yet how this process is initiated remains unclear. Using a murine model of inflammation-induced tumorigenesis, we tested the hypothesis that inflammation promotes recruitment of epigenetic proteins to chromatin, initiating methyla...

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Vydáno v:Cancer Res
Hlavní autoři: Maiuri, Ashley R., Peng, Michael, Sriramkumar, Shruthi, Kamplain, Caitlin M., DeStefano Shields, Christina E., Sears, Cynthia L., O’Hagan, Heather M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516887/
https://ncbi.nlm.nih.gov/pubmed/28522752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0056
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