DNA methyltransferase inhibition reduces inflammation-induced colon tumorigenesis

Chronic inflammation is strongly associated with an increased risk of developing colorectal cancer. DNA hypermethylation of CpG islands alters the expression of genes in cancer cells and plays an important role in carcinogenesis. Chronic inflammation is also associated with DNA methylation alteratio...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Maiuri, Ashley R., Savant, Sudha S., Podicheti, Ram, Rusch, Douglas B., O’Hagan, Heather M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791707/
https://ncbi.nlm.nih.gov/pubmed/31240997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1634986
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