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Development of Small Molecule Non-peptide Formyl Peptide Receptor (FPR) Ligands and Molecular Modeling of Their Recognition

Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) expressed on a variety of cell types.These receptors play an important role in the regulation of inflammatory reactions and sensing cellular damage. They have also been implicated in the pathogenesis of various diseases, includi...

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Detalhes bibliográficos
Publicado no:Curr Med Chem
Main Authors: Schepetkin, I. A., Khlebnikov, A.I., Giovannoni, M.P., Kirpotina, L.N., Cilibrizzi, A., Quinn, M.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791360/
https://ncbi.nlm.nih.gov/pubmed/24350845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867321666131218095521
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