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Computational Structure-activity Relationship Analysis of Small-Molecule Agonists for Human Formyl Peptide Receptors

N-formyl peptide receptors (FPR) are important in host defense. Because of the potential for FPRs as therapeutic targets, recent efforts have focused on identification of non-peptide agonists for two FPR subtypes, FPR1 and FPR2. Given that a number of specific small molecule agonists have recently b...

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Bibliografiske detaljer
Main Authors: Khlebnikov, Andrei I., Schepetkin, Igor A, Quinn, Mark T.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953788/
https://ncbi.nlm.nih.gov/pubmed/20870313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2010.09.001
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