Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1

Human N-formyl peptide receptor 1 (FPR1) is a G protein-coupled receptor (GPCR) involved in host defense and sensing cellular damage. Since structure-based ligand design for many GPCRs, including FPR1, is restricted by the lack of experimental three dimensional structures, homology modeling has been...

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Main Authors: Khlebnikov, Andrei I., Schepetkin, Igor A., Kirpotina, Liliya N., Brive, Lars, Dahlgren, Claes, Jutila, Mark A., Quinn, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314724/
https://ncbi.nlm.nih.gov/pubmed/22127612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-011-1307-x
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