Identification of Novel Small-Molecule Agonists for Human Formyl Peptide Receptors and Pharmacophore Models of Their Recognition

N-formyl peptide receptor (FPR1) and N-formyl peptide receptor-like 1 (FPRL1, now known as FPR2) are G protein-coupled receptors involved in host defense and sensing cellular dysfunction. Because of the potential for FPR1/FPR2 as a therapeutic target, our recent high-throughput screening efforts hav...

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Bibliografiset tiedot
Päätekijät: Kirpotina, Liliya N., Khlebnikov, Andrei I., Schepetkin, Igor A., Ye, Richard D., Rabiet, Marie-Josèphe, Jutila, Mark A., Quinn, Mark T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812066/
https://ncbi.nlm.nih.gov/pubmed/19903830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.060673
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