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Chlorpromazine Inhibits Miniature GABAergic Currents by Reducing the Binding and by Increasing the Unbinding Rate of GABA(A)Receptors

Recent studies have emphasized that nonequilibrium conditions of postsynaptic GABA(A) receptor (GABA(A)R) activation is a key factor in shaping the time course of IPSCs (Puia et al., 1994; Jones and Westbrook, 1995). Such nonequilibrium, resulting from extremely fast agonist time course, may affect...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Mozrzymas, Jerzy W., Barberis, Andrea, Michalak, Krystyna, Cherubini, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786064/
https://ncbi.nlm.nih.gov/pubmed/10087062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-07-02474.1999
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