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Desensitization and binding properties determine distinct α1β2γ2 and α3β2γ2 GABA(A) receptor-channel kinetic behavior

GABA(A) receptor subtypes comprising the α1 and α3 subunits change with development and have a specific anatomical localization in the adult brain. These receptor subtypes have been previously demonstrated to greatly differ in deactivation kinetics but the underlying gating mechanisms have not been...

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Detalhes bibliográficos
Main Authors: Barberis, Andrea, Mozrzymas, Jerzy W, Ortinski, Pavel I, Vicini, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950087/
https://ncbi.nlm.nih.gov/pubmed/17561840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2007.05530.x
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