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Stoichiometric analysis of the TM2 6′ phenylalanine mutation on desensitization in α1β2 and α1β2γ2 GABA(A) receptors

The presence of phenylalanine (F) at the 6′ position of transmembrane domain 2 (TM2) in the α4 subunit of α4β2 nicotinic receptors enhances desensitization. As the GABA(A) receptor affords the ability to study the influence of as few as one and as many as five Fs at this position, we have used it to...

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Detalhes bibliográficos
Main Authors: Gonzales, Eric B., Bell-Horner, Cathy L., Dibas, Mohammed I., Huang, Ren-Qi, Dillon, Glenn H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696071/
https://ncbi.nlm.nih.gov/pubmed/18162311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.11.039
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